Unrelated Match Bone Marrow Transplantation for Severe Aplastic Anemia.

DOI PubMed
  • URASE Fumiaki
    Third Department of Internal Medicine, Kinki University School of Medicine
  • ISHIKAWA Hiroyuki
    Third Department of Internal Medicine, Kinki University School of Medicine
  • KANBARA Mari
    Third Department of Internal Medicine, Kinki University School of Medicine
  • HAZU Shizuka
    Third Department of Internal Medicine, Kinki University School of Medicine
  • TSUJI Kojiro
    Third Department of Internal Medicine, Kinki University School of Medicine
  • ASHIDA Takashi
    Third Department of Internal Medicine, Kinki University School of Medicine
  • TSUBAKI Kazuo
    Third Department of Internal Medicine, Kinki University School of Medicine
  • HORIUCHI Atsushi
    Third Department of Internal Medicine, Kinki University School of Medicine

Bibliographic Information

Other Title
  • 移植前処置にＴＢＩとＴＬＩを併用し，非血縁者間骨髄移植を行った再生不良性貧血例

Search this article

Description

The results of unrelated bone marrow transplantaion (BMT) is poor because of the rejection of bone marrow graft and graft versus host disease (GVHD). However, the rate of rejection has been reported to be decreased by intensive immuno-suppressive preconditioning regimens combined with total body irradiation (TBI). We report a case of an 18-year-old male with severe aplastic anemia who received a matched BMT from an unrelated donor. The pre-conditioning regimen included cyclophosphamide (50mg/kg) for 4 days, total lymphoid irradiation (TLI: 6Gy) and TBI (5Gy). GVHD (grade 1), hemorrhage cystitis and varicella occured afte BMT but were cured. His performance status is now 100% on the Karnofsky score at 10 months after BMT.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 34 (12), 1584-1586, 1993

    The Japanese Society of Hematology

Keywords

Details 詳細情報について

Report a problem

Back to top