同種骨髄移植により血清梅毒反応が陽性化し,治療により陰性化した急性白血病症例

書誌事項

タイトル別名
  • Positive Seroconversion Syphilis in a Patient with Acute Lymphocytic Leukemia after Allogeneic Bone Marrow Transplantation
  • ドウシュ コツズイ イショク ニ ヨリ ケッセイ バイドク ハンノウ ガ ヨウ

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抄録

An acute lymphocytic leukemia patient underwent allogeneic bone marrow transplantation (BMT) from a sibling who was serologically positive for syphilis. After the donor was administered antibiotic therapy, the titration of treponema pallidum hemagglutination (TPHA) decreased from ×1260 to ×320. Thereafter, the graft consisting of mononuclear cells was transplanted. TPHA of the recipient turned positive on day +63, but became negative 1.5 years after BMT. Although the cause of the seroconversion of TPHA seemed to be the contamination of treponema to the graft, the adoptive transfer could not be ruled out as an another possible cause.

収録刊行物

  • 臨床血液

    臨床血液 38 (3), 228-230, 1997

    一般社団法人 日本血液学会

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