書誌事項
- タイトル別名
-
- Acute promyelocytic leukemia with a history of RAEB in transformation and the 15/17 translocation.
この論文をさがす
説明
A 34-year old female was admitted to our clinic because of fever and general fatigue on March 26, 1987. On admission, peripheral blood (PB) revealed pancytopenia. Bone marrow smears revealed 9.0% of promyelocytic cells with or without Auer rods. Diagnosis of RAEB in transformation was made. Chromosome study of the bone marrow cells showed t(15;17) in 3 out of 20 cells analysed. After 3 months, the leukemic cells were observed in PB and increased in number. Then the patient showed bleeding tendency and fibrin degradation products (FDP) increased up to 40 μg/ml. And the leukemic cells were over 30% in PB at the end of July, 1987. The diagnosis of APL with DIC was made.<br>To our knowledge, this is the first case of APL with a history of MDS with t(15;17).
収録刊行物
-
- 臨床血液
-
臨床血液 30 (1), 67-71, 1989
一般社団法人 日本血液学会