成人型Fanconi症候群を呈したBence Jones κ型骨髄腫の1例

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タイトル別名
  • A Case of Bence Jones Protein Kappa Type Myeloma with Adult Fanconi syndrome
  • セイヒトガタ Fanconi ショウコウグン オ テイシタ Bence Jon

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Recently we experienced adult Fanconi syndrome seemed as being secondary to Bence Jones protein kappa type myeloma.<br>The patient was a thirty-one year old man who had had glycosuria and proteinuria since about seven years. In the bone marrow were observed myeloma cells containing needle-shaped cytoplasmic inclusion bodies. Bence Jones protein kappa type was detected by urine protein immunoelectrophoresis. Kidney biopsy specimen showed remarkable deposition of protein-like bodies in proximal tubules.<br>In the future, the presence of plasma cell dyscrasia should be taken into consideration in patients with adult Fanconi syndrome.<br>However, monoclonal increase of immunoglobulin is rare in this type of myeloma, therefore, it appears necessary to detect Bence Jones protein thoroughly by such means as urine protein immunoelectrophoresis.

収録刊行物

  • 臨床血液

    臨床血液 19 (3), 234-239, 1978

    一般社団法人 日本血液学会

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