Regression of uterine cervical diffuse large B-cell lymphoma transformed from mucosa-associated lymphoid tissue lymphoma subsequent to <i>Chlamydia trachomatis</i> eradication

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  • MUTOH Toshitaka
    Department of Hematological Internal Medicine, Kokura Medical Center, National Hospital Organization
  • TAKATSUKI Hiroshi
    Department of Hematological Internal Medicine, Kokura Medical Center, National Hospital Organization
  • MANNOJI Kiyohito
    Department of Hematological Internal Medicine, Kokura Medical Center, National Hospital Organization
  • KAWAMURA Kyoko
    Department of Obstetrics and Gynecology, Kokura Medical Center, National Hospital Organization
  • OKURA Naofumi
    Department of Obstetrics and Gynecology, Kokura Medical Center, National Hospital Organization
  • OHSHIMA Koichi
    Department of Pathology, Kurume University School of Medicine

Bibliographic Information

Other Title
  • 子宮頸部MALTリンパ腫から移行しクラミジアトラコマティス除菌後に消退したびまん性大細胞型B細胞リンパ腫
  • 症例報告 子宮頸部MALTリンパ腫から移行しクラミジアトラコマティス除菌後に消退したびまん性大細胞型B細胞リンパ腫
  • ショウレイ ホウコク シキュウ ケイブ MALT リンパシュ カラ イコウ シ クラミジアトラコマティスジョキン ゴ ニ ショウタイシタ ビマンセイ ダイ サイボウガタ B サイボウ リンパシュ
  • Regression of uterine cervical diffuse large B-cell lymphoma transformed from mucosa-associated lymphoid tissue lymphoma subsequent to Chlamydia trachomatis eradication.

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Description

<p>A 37-year-old-woman was referred to our center after her uterine cervix health screening presented abnormal findings. We performed a biopsy of the uterine cervix to examine for cervical dysplasia, and diagnosed a diffuse large B-cell lymphoma transformed from mucosa-associated lymphoid tissue (MALT) lymphoma of the cervix. The patient presented with concurrent chlamydial cervicitis and received eradication therapy for Chlamydia trachomatis. Four months later, the CD20 positive abnormal lymphocyte disappeared and complete remission was achieved. MALT lymphoma is considered to correlate with infection and inflammation. Particularly, the relationship between gastric MALT lymphoma and Helicobacter pylori is well known. MALT lymphoma of the uterine cervix is rare, and its relationship with C.trachomatis infection is unknown. Further studies are warranted to investigate this association.</p>

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 58 (8), 912-916, 2017

    The Japanese Society of Hematology

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