書誌事項
- タイトル別名
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- Iatrogenic Osteomalacia: Report of Two Cases
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Case 1: An 80-year-old man presented at our hospital with pain in both knees.He had received continuous intravenous administration of saccharated ferric oxide (SFO) over a period of five years following a diagnosis of iron-deficiency anemia.Blood tests revealed hypophosphatemia (1.4 mg/dl) and high circulating levels of fibroblast growth factor 23 (FGF23) at 248.8 mg/dl.These findings led to the diagnosis of FGF23-related osteomalacia due to SFO administration.Accordingly, the treatment plan was first to discontinue SFO, which led to a decrease in pain and normalization of phosphorus and FGF23 after 1 month.Case 2: A 63-year-old woman presented at our hospital with leg pain.She had undergone total gastrectomy for gastric cancer at 36 years of age.Blood tests revealed hypocalcemia (8.3 mg/dl) and hypophosphatemia (2.2 mg/dl), and 25(OH)D at no more than 5 pg/ml.Bone X-rays showed significantly diminished bone shadowing.These findings led to a diagnosis of vitamin D-deficient osteomalacia due to impaired absorption following total gastrectomy.For therapy, she was treated with 1 μg/day oral alfacalcidol.Two months after initiating treatment, the pain improved.Conclusion: When a patient is diagnosed with unexplained pain, it is important to pay attention to the possibility of an iatrogenic etiology.
収録刊行物
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- Journal of UOEH
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Journal of UOEH 35 (1), 25-31, 2013
学校法人 産業医科大学
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詳細情報 詳細情報について
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- CRID
- 1390282680059506816
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- NII論文ID
- 110009593198
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- NII書誌ID
- AN0009832X
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- COI
- 1:STN:280:DC%2BC3svkvVWrtg%3D%3D
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- ISSN
- 21872864
- 0387821X
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- NDL書誌ID
- 024338240
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- PubMed
- 23475021
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可