A Case of Pyoderma Gangrenosum in Combination with Myelodysplastic Syndrome<BR>—A Case Report and the Consideration of Neutrophilic Dermatoses—

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  • 骨髄異形成症候群(MDS)に合併した壊疽性膿皮症の1例<BR>—症例報告とneutrophilic dermatosesに関する考察—

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A 46 year-old woman with myelodysplastic syndrome had been treated from 1983. In December 1993, she presented a painful nodule on her left forearm. This nodule subsequently ulcerated and then developed into an asymmetrical ulcer with black crust surrounded by erythema. Histologically, the epidermis was found to be necrotic and a dense infiltrate of neutrophils was present in the upper and lower dermis. From these findings, the nodule was diagnosed as pyoderma gangrenosum. The lesion disappeared with prednizolone therapy. A new nodule, however, developed on the head accompanied by fever in July 1994, and despite a repeat of the steroid therapy, there was no improvement. The patient died soon after from a cerebral infarction.<BR>In addition to a case report, we discussed the definition and scope of “neutrophilic dermatoses”.

Journal

  • Hifu no kagaku

    Hifu no kagaku 2 (4), 300-304, 2003

    Meeting of Osaka Dermatological Association/Meeting of Keiji Dermatological Association

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