書誌事項
- タイトル別名
-
- 1-Year Oral Toxicity Study of Chinese bayberry extract in F344/DuCrj Rats
- ヤマモモ チュウシュツブツ ノ 1ネンカン ハンプク トウヨ ドクセイ シケン
この論文をさがす
説明
The present report concerns results of a 1-year oral toxicity study of Chinese bayberry extract, one active component of which is myricitrin, a flavonoid. F344 rats (20rats/group both sexes) were given diet containing Chinese bayberry extract at doses of 0, 0.5, 1.5 or 5.0%. Decrease in monocytes on differential counts of WBCs and increase of reticulocytes were observed in the 1.5 and 5.0% male groups. Significant decrease in relative lung weights was apparent in the 0.5, 1.5 and 5.0% males. However, these changes were considered incidental effects. No treatment related effects were noted regarding clinical observation, body weights, food and water consumption, ophthalmologic findings, clinical chemistry and pathology. In conclusion, 1 year dietary treatment with Chinese bayberry extract at levels up to 5.0% demonstrated no toxicologically significant effects in either male or female rats. It was thus inferred that the no-observed adverse effect level (NOAEL) was up to 5.0% in both sexes.
収録刊行物
-
- 日本食品化学学会誌
-
日本食品化学学会誌 8 (2), 94-99, 2001-08-31
日本食品化学学会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390282680171883136
-
- NII論文ID
- 110007367223
-
- NII書誌ID
- AA11666400
-
- ISSN
- 21896445
- 13412094
-
- NDL書誌ID
- 5910102
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- NDLサーチ
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可
