書誌事項
- タイトル別名
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- 1-Year Oral Toxicity Study of Chinese bayberry extract in F344/DuCrj Rats
- ヤマモモ チュウシュツブツ ノ 1ネンカン ハンプク トウヨ ドクセイ シケン
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抄録
The present report concerns results of a 1-year oral toxicity study of Chinese bayberry extract, one active component of which is myricitrin, a flavonoid. F344 rats (20rats/group both sexes) were given diet containing Chinese bayberry extract at doses of 0, 0.5, 1.5 or 5.0%. Decrease in monocytes on differential counts of WBCs and increase of reticulocytes were observed in the 1.5 and 5.0% male groups. Significant decrease in relative lung weights was apparent in the 0.5, 1.5 and 5.0% males. However, these changes were considered incidental effects. No treatment related effects were noted regarding clinical observation, body weights, food and water consumption, ophthalmologic findings, clinical chemistry and pathology. In conclusion, 1 year dietary treatment with Chinese bayberry extract at levels up to 5.0% demonstrated no toxicologically significant effects in either male or female rats. It was thus inferred that the no-observed adverse effect level (NOAEL) was up to 5.0% in both sexes.
収録刊行物
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- 日本食品化学学会誌
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日本食品化学学会誌 8 (2), 94-99, 2001-08-31
日本食品化学学会
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390282680171883136
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- NII論文ID
- 110007367223
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- NII書誌ID
- AA11666400
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- ISSN
- 21896445
- 13412094
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- NDL書誌ID
- 5910102
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可