Regenerative medicine of oral tissue: clinical trial of alveolar bone regeneration and regeneration of blood vessels and peripheral nerves

DOI 14 References
  • Kagami Hideaki
    Division of Stem Cell Engineering, The Institute of Medical Science, The University of Tokyo
  • Asahina Izumi
    Department of Oral and Maxillofacial Surgery, Nagasaki University School of Dentistry
  • Agata Hideki
    Division of Stem Cell Engineering, The Institute of Medical Science, The University of Tokyo Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine
  • Narita Yuji
    Department of Clinical Cell Therapy and Tissue Engineering, Nagoya University School of Medicine
  • Yamamoto Noriyuki
    Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine
  • Okamoto Hideki
    Department of Orthopedic Surgery, Nagoya City University, Graduate School of Medical Science
  • Tohnai Iwai
    Department of Oral and Maxillofacial Surgery, Yokohama City University School of Medicine
  • Ueda Minoru
    Division of Stem Cell Engineering, The Institute of Medical Science, The University of Tokyo Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine

Bibliographic Information

Other Title
  • 口腔組織の再生医療―顎骨再生の臨床研究と血管，神経の再生について―
  • clinical trial of alveolar bone regeneration and regeneration of blood vessels and peripheral nerves
  • ―顎骨再生の臨床研究と血管，神経の再生について―

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Abstract

Recently, the concept of regenerative medicine has been attracting much attention. Regenerative medicine utilizes cells, bioactive molecules and biodegradable scaffolds to regenerate lost tissues. Since the concept of regenerative medicine does not require donor tissue, it is considered as a novel and less invasive treatment for patients. At present, the applicable tissues and defect size are limited and the regeneration of larger tissue defects after tumor resection is not feasible. However, it is expected that at least a part of current reconstructive surgery will be replaced by regenerative medicine in the future. Currently, a clinical trial of bone regeneration using mesenchymal stem cells is underway in our facility. Other than bone, blood vessels and peripheral nerves are important target tissues for regenerative medicine. In this paper, the current research activities on those tissues are also discussed.

Journal

  • Toukeibu Gan

    Toukeibu Gan 33 (3), 238-243, 2007

    Japan Society for Head and Neck Cancer

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