Clinical study on multiple primary squamous cell carcinomas of the oral cavity

Shimamoto Hiroaki, Omura Ken, Harada Hiroyuki

doi:10.5981/jjhnc.38.1

Bibliographic Information

Other Title

口腔多発扁平上皮癌症例の臨床的検討

Published: 2012

DOI

10.5981/jjhnc.38.1

Publisher: Japan Society for Head and Neck Cancer

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Description

The subjects were 35 patients diagnosed with multiple squamous cell carcinomas of the oral cavity among 709 patients with primary squamous cell carcinoma of the oral cavity. The incidence of multiple squamous cell carcinomas was 4.9%. The second and third primary carcinomas frequently developed in the buccal mucosa, mandibular gingiva, tongue and maxillary gingiva. Tumor size and invasiveness of treatment tended to decrease with progression to the second and third carcinomas. The mean interval between the first and second carcinomas was 60 months, while that between the second and third carcinomas was 24.5 months. The 10-year cumulative incidence of multiple squamous cell carcinoma of the oral cavity was 13.1%, and the five-year cumulative survival rate from the onset of the second carcinoma was 81.1%. Local recurrence rate was 37.1%, which was higher than that of solitary carcinomas. The high incidence rate and recurrence rate indicate the necessity of close and long-term follow-up after the treatment of the first carcinoma. Reduced invasiveness of treatment due to early detection was thought to lead to the preservation of oral function.

Journal

Toukeibu Gan

Toukeibu Gan 38 (1), 1-5, 2012

Japan Society for Head and Neck Cancer

Keywords

Details 詳細情報について

CRID: 1390282680200525440

NII Article ID: 130004510132; 10030815669

NII Book ID: AA11985555

DOI: 10.5981/jjhnc.38.1

ISSN: 18818382; 13495747

Web Site: https://search.jamas.or.jp/link/ui/2012224213

Text Lang: ja

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