Studies on Antibiotics. XVI. Isolation and Identification of Dihydrostreptomycin produced by a New Streptomyces, Streptomyces humidus nov. sp.
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説明
Isolation and chemical studies were carried out on an antibiotic which was produced by a new streptomyces, Streptomyces humidus nov. sp. From the physical, chemical, and microbiological properties of this antibiotic in crude state, it was found that this antibiotic belonged to the so-called streptomycin-group antibiotics, but differed from streptomycin, mannosidostreptomycin, and hydroxystreptomycin, which are produced directly by streptomycetes. This antibiotic was finally isolated as a pure crystalline sulfate. The physicochemical and microbiological properties of this sulfate and physicochemical properties of its degradation products showed that this sulfate was nothing but dihydrostreptomycin sulfate.
収録刊行物
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- Pharmaceutical Bulletin
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Pharmaceutical Bulletin 5 (4), 343-349, 1957
公益社団法人 日本薬学会