赤血球脆弱性の簡易評価に関する研究

DOI

書誌事項

タイトル別名
  • A Simple Assessment Method of Red Blood Cell Fragility

抄録

This study proposes a simple optical method for assessing red blood cell (RBC) fragility. A sodium citrate-added porcine blood was centrifuged. The RBCs contained in the upper and lower 3% of the RBC layer were collected and each sample of 1.5μL was added to saline of 0.75mL. Here we call these samples U and L groups, respectively. Each sample was added to distilled water of 0.75mL to expose the RBCs to low osmolality. The time variation in the optical power transmitted through the sample was approximated with a first order lag function and the time constant was calculated. The mean time constants of U and L groups were 20.5s and 16.3s, respectively. The difference of the time constant seems to reflect the mean fragility of RBCs contained in the samples. Furthermore, the change in the volume distribution of RBCs was also considered through the frequency analysis of the output signal.

収録刊行物

  • 生体医工学

    生体医工学 52 (Supplement), O-531-O-531, 2014

    公益社団法人 日本生体医工学会

詳細情報 詳細情報について

  • CRID
    1390282680243734656
  • NII論文ID
    130004695895
  • DOI
    10.11239/jsmbe.52.o-531
  • ISSN
    18814379
    1347443X
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

問題の指摘

ページトップへ