3次元MRI画像によるヒト眼軸長自動測定

  • 渡辺 将樹
    新潟大学脳研究所統合脳機能研究センター 新潟大学大学院自然科学研究系
  • 木竜 徹
    新潟大学大学院自然科学研究系

書誌事項

タイトル別名
  • Automatic Measurement of Axial Length of Human Eye using Three-Dimensional Magnetic Resonance Imaging
  • 3ジゲン MRI ガゾウ ニ ヨル ヒトガンジクチョウ ジドウ ソクテイ

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説明

The measurement of axial length and the evaluation of three dimensional (3D) form of an eye are essential to evaluate the mechanism of myopia progression. We propose a method of automatic measurement of axial length including adjustment of the pulse sequence of short-term scan which could suppress influence of eyeblink, using a magnetic resonance imaging (MRI) which acquires 3D images noninvasively. Acquiring T2-weighted images with 3.0 tesla MRI device and eight-channel phased-array head coil, we extracted left and right eye ball images, and then reconstructed 3D volume. The surface coordinates were calculated from 3D volume, fitting the ellipsoid model coordinates with the surface coordinates, and measured the axial length automatically. Measuring twenty one subjects, we compared the automatically measured values of axial length with the manually measured ones, then confirmed significant elongation in the axial length of myopia compared with that of emmetropia. Furthermore, there were no significant differences (p<0.05) between the means of automatic measurements and the manual ones. Accordingly, the automatic measurement process of axial length could be a tool for the elucidation of the mechanism of myopia progression, which would be suitable for evaluating the axial length easily and noninvasively.

収録刊行物

  • 生体医工学

    生体医工学 49 (1), 11-16, 2011

    公益社団法人 日本生体医工学会

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