術中での無染色神経イメージングを目指したコヒーレントアンチストークスラマン散乱硬性鏡の開発

DOI

書誌事項

タイトル別名
  • Development of coherent anti-Stokes Raman scattering rigid endoscope for label-free nerve imaging during an operation

抄録

<p>We have developed a coherent anti-Stokes Raman scattering (CARS) rigid endoscope for label-free nerve imaging during an operation. The CARS rigid endoscope consists of a single-mode fiber which delivers two color lasers, a galvano scanning system, and homemade ϕ12 mm lens tubes which include two relay lenses and an objective lens. The label-free imaging of rat sciatic nerve is demonstrated. To attain CARS image with high- speed, correcting chromatic aberration is focused on. The split between the focal spots of two lasers passed through the lens tubes is 21 μm and a numerical simulation shows that the intensity of CARS signal by correcting the chromatic aberration is 2.3 times as strong as non-correcting. The rigid endoscope has been modified to suppress the chromatic aberration by using two single-mode fibers which deliver the two lasers individually. The experimental result shows the increase of CARS intensity at least 1.5 times.</p>

収録刊行物

  • 生体医工学

    生体医工学 54Annual (28PM-Abstract), S344-S344, 2016

    公益社団法人 日本生体医工学会

詳細情報 詳細情報について

  • CRID
    1390282680246262272
  • NII論文ID
    130005285405
  • DOI
    10.11239/jsmbe.54annual.s344
  • ISSN
    18814379
    1347443X
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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