A CASE OF ISOLATED ACTH DEFICIENCY WITH SEVERE HYPOGLYCEMIA

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  • M. KOYANO HAJIME
    DIVISION OF ENDOCRINOLOGY AND DIABETES, DEPARTMENT OF MEDICINE, JUNTENDO UNIVERSITY URAYASU HOSPITAL
  • SATO JUNKO
    DIVISION OF ENDOCRINOLOGY AND DIABETES, DEPARTMENT OF MEDICINE, JUNTENDO UNIVERSITY URAYASU HOSPITAL
  • YOSHII SHOUKO
    DIVISION OF ENDOCRINOLOGY AND DIABETES, DEPARTMENT OF MEDICINE, JUNTENDO UNIVERSITY URAYASU HOSPITAL
  • KOIKE YOSHIE
    DIVISION OF ENDOCRINOLOGY AND DIABETES, DEPARTMENT OF MEDICINE, JUNTENDO UNIVERSITY URAYASU HOSPITAL

Bibliographic Information

Other Title
  • 低血糖による意識障害で発見されたACTH単独欠損症の1例
  • 症例報告 低血糖による意識障害で発見されたACTH単独欠損症の1例 : 疫学調査をふまえた自発性低血糖症の鑑別診断
  • ショウレイ ホウコク テイケットウ ニ ヨル イシキ ショウガイ デ ハッケン サレタ ACTH タンドク ケッソンショウ ノ 1レイ : エキガク チョウサ オ フマエタ ジハツセイ テイケットウショウ ノ カンベツ シンダン
  • 疫学調査をふまえた自発性低血糖症の鑑別診断

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A 42-year-old woman was admitted to our hospital with severe hypoglycemia. She had undetectable plasma ACTH and cortisol before and after CRH stimulation. There was no evidence of other pituitary hormone deficiency. Thus, we diagnosed her with isolated ACTH deficiency (IAD). Replacement with hydrocortisone efficiently prevented hypoglycemia. Recent epidemiological studies in Japan showed that IAD should be considered as an important disease causing hypoglycemia well as insulinoma.

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