Effects of Overcrowding Stress on Hair Growth in Guinea Pigs

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  • ストレスが被毛成長に及ぼす影響について
  • ストレス ガ ヒモウ セイチョウ ニ オヨボス エイキョウ ニ ツイテ

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Stress is considered to be a major social problem, influencing mental and physical health. In the present study, the influences of stress on hair growth were studied in guinea pigs, who were subjected to overcrowding stress, which is considered to be a social stress. After 7 days of overcrowding stress, the back hair was shaved. At 1, 4 and 8 days after shaving, the lengths and diameters of regrowing hairs were measured, and they were microscopically observed. Furthermore, activities of several enzymes in homogenates of skin samples were measured before and after the stress treatment. Both the length and diameter of the hairs remarkably declined in the stress group compared with those of the control group (p<0.001). Microscopically, ringed stripes were seen in the affected hairs, indicating a qualitative deterioration of the hairs. Activities of all of sulfhydryl oxidase, alkaline phosphatase, and gamma-glutamyl transpeptidase in the back skin were significantly reduced in the stress group (p<0.01). These results suggest that social stress such as the overcrowding stress may influence growth and quality of hair.



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