Biologically Active Principles of Crude Drugs Analgesic and Anti-inflammatory Effects of "Keigai (Shizonepeta tenuifolia BRIQ)"

DOI Web Site Web Site 3 Citations

Bibliographic Information

Other Title
  • 生薬の生物活性成分に関する研究ケイガイの鎮痛および抗炎症作用
  • ショウヤク ノ セイブツ カッセイ セイブン ニカンスルケンキュウ ケイガイ

Search this article

Description

Screening tests for the analgesic and anti-inflammatory effects of some crude drugs containing volatile oils were carried out by the Whittle method. The results showed that the essential oil fraction of "Keigai (Shizonepeta tenuifolia BRIQ)" inhibited strongly both writhing and capillary permeability in mice. The essential oil of "Keigai" was found to consist mainly of d-menthone (42.9%) and l-pulegone (33.9%). Chemical separation of the essential oil fraction was carried out to clarify the active principles. The analgesic activity was found in d-menthone, and an anti-inflammatory effect was observed in l-pulegone.

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 100 (7), 713-717, 1980

    The Pharmaceutical Society of Japan

Citations (3)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top