書誌事項
- タイトル別名
-
- Quantitative Analysis and Pharmaco-Toxicity of Cannabinoids in Commercially Available Cannabis Seeds
- シハン ノ タイマ シュシ チュウ ノ カンナビノイド ノ テイリョウ ト ソ
この論文をさがす
抄録
△9-Tetrahydrocannabinol (△9-THC), cannabinol, cannabidiol and cannabichromene were detected in commercially available cannabis seeds by silica gel TLC and gas chromatography. These cannabinoids existed in rather high content (0.10-2.02mg/100g of seeds) in the feed for birds, especially bracts (82.3-441mg/100g). When the suspension prepared from the benzene washing solution of cannabis seeds, BenW, was administered at a dose of 3mg/kg corresponding to △9-THC into a mouse, i.v., BenW caused hypothermia, catalepsy, pentobarbital-induced sleep prolongation and suppression of locomotor activity. These pharmacological activities of BenW were significantly higher than those of △9-THC (3mg/kg, i.v.). These results may indicate the necessity to reconsider the present regulations on marihuana.
収録刊行物
-
- 薬学雑誌
-
薬学雑誌 118 (9), 408-414, 1998
公益社団法人 日本薬学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282681130762496
-
- NII論文ID
- 110003649170
-
- NII書誌ID
- AN00284903
-
- ISSN
- 13475231
- 00316903
-
- NDL書誌ID
- 4551447
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可