細菌内毒素による発熱ウサギを用いた漢方方剤の解熱作用の検討

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書誌事項

タイトル別名
  • Antipyretic Effects of Traditional Chinese Medicines in Bacterial Endotoxin-Induced Febrile Rabbits
  • サイキンナイ ドクソ ニ ヨル ハツネツ ウサギ オ モチイタ カンポウ ホウ

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抄録

The antipyretic effects of oral administration of eight traditional Chinese medicines (dried extracts) were tested in febrile rabbits injected with bacterial pyrogen, lipopolysaccharide (LPS) 0.05 μg/kg (i.v.). The traditional Chinese medicines were given 0.6-2 g/10 ml/kg (p.o.) simultaneously with LPS. The most potent antipyretic effect was observed in Dai-jyoki-to (Tachen-chi-tang). The moderate antipyretic effects were observed in Tokisyakuyaku-san (Tang-kuei-shao-yao-san) and Syo-saiko-to (Hssiao-chai-hutang). Koso-san (Hsiang-su-san), Oren-gedoku-to (Huang-lien-chieh-tu-tan), Gorei-san (Wu-ling-san), Kakkon-to (Ko-ken-tang) and Byakkoka-ninjin-to (Pai-hu-chia-jen-sheng-tang) showed no effects.

収録刊行物

  • 薬学雑誌

    薬学雑誌 112 (2), 129-134, 1992

    公益社団法人 日本薬学会

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