書誌事項
- タイトル別名
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- A Potential Mechanism for Spontaneous Oscillation in the Abnormal Retina
- Symposium Review 病変網膜における自発振動活動発生メカニズム
- Symposium Review ビョウヘン モウマク ニ オケル ジハツ シンドウ カツドウ ハッセイ メカニズム
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抄録
Rhythmic neural activities are observed in many brain regions, and these are considered to play an important role in neural information processing. On the other hand, distinct rhythmic neural activities emerge under several pathological conditions, suggesting that rhythmic neural activity has a close relation to brain function and dysfunction. In many pathological cases, the intrinsic property of unusual rhythm generation in a neuron or a neuronal network is prevented under normal conditions, but released by the pathological condition. Therefore, it may be useful to explore which conditions determine rhythm generation in order to understand the mechanisms of brain function/dysfunction. The pathological retina in retinal degeneration exhibits rhythmic neural activity not observed in the healthy retina. In this review, we first provide a brief introduction to the possible mechanisms of rhythm generation in a neural system. Then we introduce experimental evidence of rhythm generation in the pathological retina, as well as two hypotheses regarding this mechanism. Finally, we raise several issues to be solved for the further understanding of pathological rhythm generation.<br>
収録刊行物
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- 薬学雑誌
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薬学雑誌 138 (5), 685-692, 2018-05-01
公益社団法人 日本薬学会
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詳細情報 詳細情報について
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- CRID
- 1390282681192409856
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- NII論文ID
- 130006729440
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- NII書誌ID
- AN00284903
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- ISSN
- 13475231
- 00316903
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- NDL書誌ID
- 029035541
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- PubMed
- 29710014
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可