ブラックマッペのアンジオテンシンI変換酵素阻害因子の検索 第2報

書誌事項

タイトル別名
  • Angiotensin I-Converting Enzyme Inhibitory Substances in Black Matpe.
  • ブラック マッペ ノ アンジオテンシン 1 ヘンカン コウソ ソガイ インシ ノ ケンサク ダイ2ホウ

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説明

ACE inhibitory substances in black matpe constituted a hydrophilic group with a molecular weight of about 400-800, estimated by gel filtration on a Sephadex G-15 column. These inhibitory substances could not be separated using reverse-phase HPLC, gel filtration or ion exchange columns. The ACE inhibitory substances contained phytic acid, which when extracted had 40% of the total activity. When the ACE inhibitory substances were analyzed by TLC, some ninhydrin-positive spots were observed, whereas the phytic acid fraction contained no ninhydrin-positive spots. These results suggest that the substances are a mixture of phytic acid and ninhydrin-positive material.

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