Effect of Sex Hormones on the Activity of Protein Kinases in Rat Ventral Prostate and Uterus
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- ICHII SHOGO
- Division of Physiology, Institute of Steroid Research, Tottori University School of Medicine
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- IWANAGA YUKIO
- Division of Physiology, Institute of Steroid Research, Tottori University School of Medicine
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- IKEDA AKEMI
- Division of Physiology, Institute of Steroid Research, Tottori University School of Medicine
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説明
To elucidate the physiological role of cAMP-dependent and -independent protein kinase and cAMP-binding protein in regulation of cellular function and metabolism, activity of the protein kinases and capacity of the cAMP-binding protein were assayed in the ventral prostate and the uterus from rats of various hormonal statuses. Castration caused a significant elevation in the activity of both cAMP-dependent and -independent protein kinase and administration of testosterone to castrated rats abolished the effect of castration on the enzyme activity. In the uterus, administration of estradiol to immature rats evoked a significant decrease in the cAMP-dependent activity but not in the cAMP-independent activity of the enzyme. Deprival of the sex hormones caused an increase in the cAMP-binding capacity in both the ventral prostate and uterus. Physiological implications of these observations were discussed.
収録刊行物
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- Endocrinologia Japonica
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Endocrinologia Japonica 20 (1), 33-37, 1973
一般社団法人 日本内分泌学会
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詳細情報 詳細情報について
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- CRID
- 1390282681274365824
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- NII論文ID
- 130000956634
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- NII書誌ID
- AA00635052
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- ISSN
- 21856370
- 00137219
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- NDL書誌ID
- 7672854
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- PubMed
- 4353250
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可