書誌事項
- タイトル別名
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- Hepatocellular Carcinoma in a Patient with Chronic Hepatitis C 6 Years after Complete Response to IFN Treatment: A Case Report and Review of the Literature.
- インターフェロン リョウホウ チョコウゴ 6ネンメ ニ カン サイボウ ガン ガ ミトメラレタ Cガタ マンセイ カンエン ノ 1 セツジョレイ : ホンポウ ホウコクレイ モ フクメテ
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抄録
A 60-year-old man diagnosed with chronic active hepatitis with hepatitis C virus infection was treated with interferon (IFN)-alpha. A successful response was obtained with normalization of serum alanine aminotransferase (ALT) and the disappearance of serum hepatitis C virus-ribonucleic acid (HCV-RNA). Serum ALT remained within normal levels and serum HCV-RNA was not detected during observation. Six years later, the level of serum PIVKA-II increased and hepatocellular carcinoma (HCC) was detected by CT examination. Partial hepatectomy of segment 4 was performed following transcatheter arterial embolization. Histological examination of the surgical specimen showed moderately differentiated HCC, and chronic hepatitis, bridging fibrosis with mild activity of necro-inflammatory reaction. These results suggest that even patients with chronic hepatitis C infection who show complete response to interferon therapy should be followed up at 3 to 6 month intervals associated with examinations for serum tumor markers and ultrasonographic screening for the potential development of HCC.
収録刊行物
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- 北関東医学
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北関東医学 51 (6), 395-399, 2001
北関東医学会
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390282681316032512
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- NII論文ID
- 130000874404
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- NII書誌ID
- AN10585677
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- ISSN
- 18811191
- 13432826
- http://id.crossref.org/issn/13432826
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- NDL書誌ID
- 026778459
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可