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Shedding of herpes simplex virus type 1 into saliva after surgery for oral and genital or urological cancer parients.
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- KAMEYAMA TADAMITSU
- Department of Oral Surgery Kurume University School of Medicine
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- HAIKATA KOJI
- Department of Oral Surgery Kurume University School of Medicine
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- NAKAMURA YOSHIAKI
- Department of Oral Surgery Kurume University School of Medicine
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- MURASE HIROSHI
- Department of Oral Surgery Kurume University School of Medicine
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- YAMAMOTO SHIGERU
- Department of Virology Kurume University School of Medicine
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Description
The shedding of herpes simplex virus type-1 (HSV-1) into the saliva was compared in 28 patients with oral cancer and 26 patients with genital or urological cancer. All subjects tested positive for HSV-1 specific antibody. A statistically significant (p<0.001) difference was found: infectious viruses were isolated from 12 (39.8%) of the oral cancer patients versus only 2 (7.6%) of the genital or urological patients. This indicates that direct stimulation of peripheral nerves during surgery was responsible for the greater reactivation of HSV-1.
Journal
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- The Kurume Medical Journal
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The Kurume Medical Journal 36 (3), 117-121, 1989
Kurume University School of Medicine
