早期アルツハイマー型痴呆診断支援システム（ＶＳＲＡＤ）における撮像方法の検討

DOI Web Site PubMed 被引用文献5件 参考文献10件

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  • Examination of an Imaging Method in Early Alzheimer Disease Diagnosis Support System (VSRAD)
  • ソウキ アルツハイマーガタ チホウ シンダン シエン システム VSRAD ニ オケル サツゾウ ホウホウ ノ ケントウ

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The use of voxel-based morphometry (VBM) has recently become a popular tool for the early diagnosis of Alzheimer disease. The Voxel-Based Specific Regional Analysis System for Alzheimer's Disease (VSRAD) is a clinically useful VBM that employs MRI. However, there has been insufficient information about the influence of the image pickup apparatus and imaging conditions in terms of the value calculated by the sensitivity correction. We therefore reviewed this problem in a volunteer who provided consent. We were able to confirm reproducibility under the same conditions. When changing the image pickup apparatus and conditions, the average Z-score of 0.18±0.21 became larger, and the change in Z-score increased when imaging was done in the axial plane. Further, the average Z-score of 0.06±0.21 for sensitivity correction use was high on average by 0.19±0.16 for phased-array uniformity enhancement (PURE) and low for surface coil intensity correction (SCIC).

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