ラット椎骨動脈経由の一酸化窒素合成酵素(NOS)および血管作用性腸管ペプチド(VIP)陽性神経による独自の発達様相

DOI 日本農学文献記事索引 Web Site Web Site 参考文献31件
  • ANDO Koichi
    Biological Laboratory, Department of Applied Chemistry and Biochemistry, Faculty of Engineering, Kyushu Sangyo University
  • YOSHIDA Souta
    Biological Laboratory, Department of Applied Chemistry and Biochemistry, Faculty of Engineering, Kyushu Sangyo University
  • YAMAUCHI Hitoshi
    Biological Laboratory, Department of Applied Chemistry and Biochemistry, Faculty of Engineering, Kyushu Sangyo University
  • KUBO Shinji
    Biological Laboratory, Department of Applied Chemistry and Biochemistry, Faculty of Engineering, Kyushu Sangyo University
  • KUSABA Haruo
    Muromi Animal Hospital

書誌事項

タイトル別名
  • Separate Development of Nitric Oxide Synthase- and Vasoactive Intestinal Polypeptide-Immunoreactive Nerves Arising from the Vertebral Artery in the Rat

この論文をさがす

抄録

Development of nitric oxide synthase (NOS)-and vasoactive intestinal polypeptide (VIP)-immunoreactive (-IR) nerves supplying the basilar and vertebral arteries (BA and VA) was investigated in White Wistar rats, using double immunohistochemistry. NOS-IR and VIP-IR nerves via the anterior circulation (AC), which mostly expressed NO+/VIP+, extended to the BA during the second postnatal week, and usually reached as far as the rostral two third of the BA on PND 20. NOS-IR nerves were completely lack in the cBA and the VA on PND10, and often absent from these arterial regions even at PND 20. Nevertheless, a small number of VIP+/NOS- nerves were localized in the walls from the caudal BA (cBA) to the VA on PND 5. On PND 20, they frequently met with the descending NOS-IR and VIP-IR nerves via the AC around the lower portion of the middle BA. Fiber bundles containing NOS+/VIP+ axons were first visualized on the caudal VA at PND 30 and observed frequently at PND 80, with a distinct increase in number of NOS-IR and VIP-IR nerves supplying the cBA and the VA. Thus, NOS-IR nerves coming from the VA develop through its own characteristic sequence that lags markedly behind the time of appearance for VIP-IR nerves from the same vascular route and for NOS-IR and VIP-IR nerves via the AC.<br>

収録刊行物

参考文献 (31)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ