Metabolic pathway for 2-keto-L-gulonic acid formation in Gluconobacter melanogenus IFO 3293.

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The L-sorbosone pathway for 2-keto-L-gulonic acid (2KGA) formation from L-sorbose in Gluconobacter melanogenus IFO 3293 was confirmed. L-Sorbose dehydrogenase, which catalyzes the conversion of L-sorbose to L-sorbosone, was found in the membrane fraction of the microorganism, and L-sorbosone dehydrogenase in the cytosol fraction. The latter enzyme requires NAD or NADP as a cofactor.<br> 2KGA was reduced to L-idonic acid by 2KGA reductase, but L-idonic acid was re-oxidized to 2KGA by membrane-bound L-idonate dehydrogenase.

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詳細情報 詳細情報について

  • CRID
    1390282681440530816
  • NII論文ID
    110006324923
  • NII書誌ID
    AA00515312
  • DOI
    10.1271/bbb1961.54.1211
  • COI
    1:CAS:528:DyaK3cXlt12isbw%3D
  • ISSN
    18811280
    00021369
    http://id.crossref.org/issn/00021369
  • 本文言語コード
    en
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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