Synthesis and Activity of Pyrimidinylpropenamide Antibiotics: The Alkyl Analogues of Sparsomycin
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- NAKAJIMA Noriyuki
- <i>Biotechnology Research Center, Toyama Prefectural University</i>
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- ENOMOTO Takeshi
- <i>Biotechnology Research Center, Toyama Prefectural University</i>
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- WATANABE Takehiro
- <i>Biotechnology Research Center, Toyama Prefectural University</i>
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- MATSUURA Nobuyasu
- <i>Biotechnology Research Center, Toyama Prefectural University</i>
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- UBUKATA Makoto
- <i>Biotechnology Research Center, Toyama Prefectural University</i>
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抄録
Facile syntheses of sparsomycin (3) and its four analogues (4-7) based on diastereoselective oxidation of sulfide, sulfenylation, and coupling of 6-methyluracylacryllic acid with monooxodithioacetal amine, are described. Studies on the biological activity of morphological reversion on srcts-NRK cells were also carried out.<br>
収録刊行物
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- Ｂｉｏｓｃｉｅｎｃｅ， Ｂｉｏｔｅｃｈｎｏｌｏｇｙ， ａｎｄ Ｂｉｏｃｈｅｍｉｓｔｒｙ
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Ｂｉｏｓｃｉｅｎｃｅ， Ｂｉｏｔｅｃｈｎｏｌｏｇｙ， ａｎｄ Ｂｉｏｃｈｅｍｉｓｔｒｙ 67 (12), 2556-2566, 2003
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390282681449875712
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- NII論文ID
- 110002694020
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- NII書誌ID
- AA10824164
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 6795094
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- PubMed
- 14730133
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可