Six New Chalcones from Angelica keiskei Inducing Adiponectin Production in 3T3-L1 Adipocytes
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- OHNOGI Hiromu
- Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine Takara Bio Inc. Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine Takara Bio Inc.
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- KUDO Yoko
- Takara Bio Inc. Takara Bio Inc.
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- TAHARA Kenichi
- Takara Bio Inc. Takara Bio Inc.
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- SUGIYAMA Katsumi
- Takara Bio Inc. Takara Bio Inc.
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- ENOKI Tatsuji
- Takara Bio Inc. Takara Bio Inc.
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- HAYAMI Shoko
- Takara Bio Inc. Takara Bio Inc.
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- SAGAWA Hiroaki
- Takara Bio Inc. Takara Bio Inc.
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- TANIMURA Yuko
- Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine
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- AOI Wataru
- Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine Laboratory of Health Science, Kyoto Prefectural University Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine Laboratory of Health Science, Kyoto Prefectural University
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- NAITO Yuji
- Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine
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- KATO Ikunoshin
- Takara Bio Inc. Takara Bio Inc.
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- YOSHIKAWA Toshikazu
- Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine
書誌事項
- タイトル別名
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- Six New Chalcones from <i>Angelica keiskei</i> Inducing Adiponectin Production in 3T3-L1 Adipocytes
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抄録
Angelica keiskei (Ashitaba in Japanese), a traditional herb in Japan, contains abundant prenylated chalcones. It has been reported that the chalcones from A. keiskei showed such bioactivities as anti-bacterial, anti-cancer and anti-diabetic effects. Xanthoangelol, 4-hydroxyderricin and six new chalcones were isolated in this study from an ethanol extract of A. keiskei by octadecyl silyl (ODS) and silica gel chromatography, and identified by 1D- and 2D-nuclear magnetic resonance (NMR) and high-resolution mass spectrometric analyses. The chalcones from A. keiskei markedly increased the expression of the adiponectin gene and the production of adiponectin in 3T3-L1 adipocytes. These results suggest that the chalcones from A. keiskei might be useful for preventing the metabolic syndrome.
収録刊行物
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- Bioscience, Biotechnology, and Biochemistry
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Bioscience, Biotechnology, and Biochemistry 76 (5), 961-966, 2012
公益社団法人 日本農芸化学会
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詳細情報 詳細情報について
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- CRID
- 1390282681455011200
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- NII論文ID
- 10030752882
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- NII書誌ID
- AA10824164
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- COI
- 1:STN:280:DC%2BC38jltlOnsA%3D%3D
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- ISSN
- 13476947
- 09168451
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- NDL書誌ID
- 023681934
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- PubMed
- 22738967
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可