Differential Expression of Virulence and Stress Fitness Genes during Interaction between Listeria monocytogenes and Bifidobacterium longum

DOI Web Site Web Site PubMed 参考文献55件
  • TAN Qianglai
    State Key Laboratory of Food Science and Technology, Nanchang University State Key Laboratory of Food Science and Technology, Nanchang University
  • XU Hengyi
    State Key Laboratory of Food Science and Technology, Nanchang University State Key Laboratory of Food Science and Technology, Nanchang University
  • CHEN Tingtao
    Jiangxi-OAI Joint Research Institute, Nanchang University Jiangxi-OAI Joint Research Institute, Nanchang University
  • LI Peng
    State Key Laboratory of Food Science and Technology, Nanchang University State Key Laboratory of Food Science and Technology, Nanchang University
  • AGUILAR Zoraida P.
    Ocean NanoTech LLC Ocean NanoTech LLC
  • XU Di
    State Key Laboratory of Food Science and Technology, Nanchang University State Key Laboratory of Food Science and Technology, Nanchang University
  • MING Xing
    State Key Laboratory of Food Science and Technology, Nanchang University State Key Laboratory of Food Science and Technology, Nanchang University
  • XU Feng
    Jiangxi-OAI Joint Research Institute, Nanchang University Jiangxi-OAI Joint Research Institute, Nanchang University
  • WEI Hua
    State Key Laboratory of Food Science and Technology, Nanchang University State Key Laboratory of Food Science and Technology, Nanchang University

書誌事項

タイトル別名
  • Differential Expression of Virulence and Stress Fitness Genes during Interaction between <I>Listeria monocytogenes</I> and <I>Bifidobacterium longum</I>

この論文をさがす

抄録

Bifidobacterium is well known to have an inhibitory effect on the survival, growth, and proliferation of various foodborne pathogens, but the mechanism of the molecular action of B. longum in blocking the invasion of Listeria monocytogenes is not yet well defined. In the present study, following RNA extraction and cDNA synthesis, differential expression of virulence and stress fitness genes in L. monocytogenes and B. longum was determined by real-time PCR. The results indicate that L. monocytogenes virulence factors, including actA, hly, inlA, and plcA, showed significantly downregulated expression during co-incubation of B. longum and L. monocytogenes in phosphate-buffered saline. The relative mRNA levels of oppA and serpin, two stress fitness genes in B. longum, were significantly higher than for the control group. These results indicate that downregulation of L. monocytogenes virulence factors during co-incubation with B. longum might be responsible for the inhibitory effects.

収録刊行物

参考文献 (55)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ