Clinical evaluation of TL-102M in stomatitis

DOI Open Access
  • OHTANI Takatoshi
    Oral Surgery, School of Medicine, Yokohama City University
  • TASHIRO Hideo
    Oral Surgery, School of Medicine, Yokohama City University First Department of Oral Surgery, Faculty of Dntistry Kyushu University
  • SHIODA Shigetoshi
    Oral Surgery, School of Medicine, Yokohama City University The First Department of Oral Surgery, Faculty of Dentistry, Tokyo Medical and Dental University
  • SHIOIRI Shigeaki
    Oral Surgery, School of Medicine, Yokohama City University The First Department of Oral Surgery, Faculty of Dentistry, Tokyo Medical and Dental University

Bibliographic Information

Other Title
  • TL‐102Mの口内炎に対する臨床試験成績  ケナログとの比較
  • ケナログ<SUP>®</SUP>との比較

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Description

A comparative clinical trial of TL-102M (adhesive powder preparation containing beclomethasone dipropionate) and Kenalog in patients with erosive or ulcerating stomatitis was performed cooperatively in 7 institutions.<BR>The results could be summarized as follows:<BR>1. The degree of overall improvement more than ‘effective’ was 80.6% in TL-102M treated group and 51.9% in Kenalog treated group, providing a significant difference in favor of TL-102M (P<0.05, X2-test).<BR>2. No adverse reactions were noted in either the TL-102M or Kenalog groups.<BR>3. The rate of overall impression more than ‘good’ by patient was 93.3% in TL-102 group and 70.4% in Kenalog group, indicating a favorable patient's impression in TL-102M group (P<0.10, X2-test).<BR>4. The degree of usefulness more than ‘useful’ was 90.3% in TL-102M group and 63.0% in Kenalog group. A significantly superior result was obtaned in TL-102M group (P<0.05, X2-test).<BR>From these results mentioned above, TL-102M was concluded to be effective, highly safe, and useful drug for treating stomatitis accompanying erosion or ulcer.

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Details 詳細情報について

  • CRID
    1390282681504011008
  • NII Article ID
    130001358337
  • DOI
    10.5794/jjoms.30.705
  • ISSN
    21861579
    00215163
  • Text Lang
    ja
  • Data Source
    • JaLC
    • Crossref
    • CiNii Articles
    • OpenAIRE
  • Abstract License Flag
    Disallowed

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