書誌事項
- タイトル別名
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- Cure of a case of osteonecrosis of the mandible associated with an oral bisphosphonate
- ケイコウ ビスフォスフォネート セイザイ ニ カンレンシタ カガクコツ エシ ノ チユ ケイケン
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説明
We report a case of osteonecrosis of the mandible associated with an oral bisphosphonate (BP) in apatient with osteoporosis and describe its cure.<BR>A 84-year-old woman received oral alendronate sodium hydrate from September 2004 through April 2006. Shewas referred to our department because of a fistula that developed after extraction of the lower right first and secondpremolars in April 2006 by her dentist. Physical examination revealed diffuse swelling of the right mandible, and hypoesthesia was present in the right mental region. Imaging of the lesion revealed an extensive radiolucentarea and a tumor-like mass in the right side of the mandible. Antibiotic therapy was started, and initial biopsy andexcisional biopsy were carried out to rule out malignant lesions. Histopathological examination showed granulationtissue and bone necrosis. BP-associated osteonecrosis of the jaw was diagnosed. BP medication was withdrawn, and conservative therapy was performed. Cure of the lesion, including bone regeneration, was observed 1year later.
収録刊行物
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- 日本口腔外科学会雑誌
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日本口腔外科学会雑誌 54 (4), 243-247, 2008
社団法人 日本口腔外科学会
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詳細情報 詳細情報について
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- CRID
- 1390282681508319616
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- NII論文ID
- 10027088395
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- NII書誌ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL書誌ID
- 9497533
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
