書誌事項
- タイトル別名
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- A case of methotrexate-associated lymphoproliferative disorders arising in the maxilla in a patient with juvenile idiopathic arthritis in adulthood
- セイジンキ ジャクネンセイ トクハツセイ カンセツエン カンジャ ノ ウワアゴ ニ ハッセイ シタ メトトレキサート カンレン リンパ ゾウショクセイ シッカン ノ 1レイ
- A case of methotrexate-associated lymphoproliferative disorders in the maxilla in a patient with juvenile idiopathic arthritis in adulthood
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Methotrexate (MTX) is a key drug widely used to treat rheumatoid arthritis. However, several reports have recently described cases of MTX-associated lymphoproliferative disorders (MTX-LPD). We report a case of MTX-LPD arising in the maxilla of a patient with juvenile idiopathic arthritis in adulthood.<br>A 40-year-old woman was referred to our clinic for the treatment of pain in the anterior maxillary gingiva. She had had juvenile idiopathic arthritis in adulthood and had received MTX for 4 years. On clinical examination, a swelling was noted at the incisal region of the maxilla. CT imaging showed a diffuse bone defect around the roots of the maxillary incisors. Antibiotic therapy had no effect on the lesion, and a biopsy was carried out. The histopathological diagnosis was diffuse large B cell lymphoma. After discussion with her physician, we suspected MTX-LPD and directed her to stop taking MTX. After stopping MTX, the lesion disappeared.
収録刊行物
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- 日本口腔外科学会雑誌
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日本口腔外科学会雑誌 58 (9), 550-554, 2012
社団法人 日本口腔外科学会
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詳細情報 詳細情報について
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- CRID
- 1390282681508344320
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- NII論文ID
- 10031144939
- 130004707925
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- NII書誌ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL書誌ID
- 024020023
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可