A case of inflammatory myofibroblastic tumor of the mandible
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- AOTA Keiko
- Department of Dentistry and Oral Surgery, Tenri Hospital
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- YUI Shumpei
- Department of Dentistry and Oral Surgery, Tenri Hospital
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- ADACHI Minoru
- Department of Dentistry and Oral Surgery, Tenri Hospital
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- SHIMIZU Hidetaka
- Second Department of Oral and Maxillofacial Surgery, Osaka University Graduate School of Dentistry
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- KINOSHITA Fumio
- Department of Dentistry and Oral Surgery, Tenri Hospital
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- YURA Yoshiaki
- Second Department of Oral and Maxillofacial Surgery, Osaka University Graduate School of Dentistry
Bibliographic Information
- Other Title
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- 下顎骨に発生した炎症性筋線維芽細胞性腫ようの1例
- ショウレイ ホウコク カガクコツ ニ ハッセイ シタ エンショウセイキン センイ ガ サイボウセイ シュヨウ ノ 1レイ
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Abstract
Inflammatory myofibroblastic tumor (IMT) is a spindle cell proliferation with a characteristic fibroinflammatorv appearance. originallv referred to as an inflammatory pseudotumor, plasma cell granuloma, andxanthomatous pseudotumor. We report a case of IMT of the mandible in a 83-year-old woman. The patient had a tumor in the right side of the mandible, measuring 30×30×20mm. Magnetic resonance imaging showed a lesion with high signal intensity on T2-weighted images and homogeneous enhancement. Histological examination of the surgically removed lesion showed that the tumor was composed of loosely arrayed spindle cells in a background of abundant blood vessels and chronic reactive inflammatory cells, including lymphocytes, plasma cells, neutrophils, and eosinophilic leukocytes. The tumor was reactive for vimentin and actin and negative for desmin, S-100, CD31, CD34, keratin, CAM 5.2, EMA, Ki-67, and ALK 1. Because IMT can be confused with other reactive processes as well as with potentially malignant neoplasms, distinguishing these tumors from histologically similar entities plays an important role in assuring appropriate disease management.
Journal
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- Japanese Journal of Oral and Maxillofacial Surgery
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Japanese Journal of Oral and Maxillofacial Surgery 51 (2), 89-92, 2005
Japanese Society of Oral and Maxillofacial Surgeons
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Details 詳細情報について
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- CRID
- 1390282681509741696
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- NII Article ID
- 10015546468
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- NII Book ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL BIB ID
- 7289241
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed