書誌事項
- タイトル別名
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- A case of dedifferentiated carcinoma occurring in adenoid cystic carcinoma of the submandibular gland
- ガク カセン ゲンパツ ダツブンカガタセン ヨウノウホウガン ノ 1レイ
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説明
Dedifferentiated carcinoma is defined as the abrupt transformation of a low-grade, well-differentiated tumor into a tumor of high malignancy. Because the transformed cells are highly aggressive, recurrence and metastasis frequently occur.<br>We report a case of dedifferentiated carcinoma in adenoid cystic carcinoma of the submandibular gland with multiple metastases to the cervical lymph nodes and distant metastasis to the ileum.<br>A 73-year-old woman was referred to our hospital because of submandibular gland carcinoma with multiple lymph node metastases. In another clinic, adenocarcinoma was pathologically diagnosed on lymph node biopsy. A surgically resected specimen showed that the tumor was composed of both a cribriform pattern of conventional low-grade adenoid cystic carcinoma and a high-grade dedifferentiated carcinoma. The lesion was thus a dedifferentiated carcinoma. Lymph node metastases contained dedifferentiated components. One year and a half after the operation, the tumor metastasized to the small intestine (ileum) . The tumor in the ileum was also pathologically diagnosed as a high-grade dedifferentiated carcinoma.
収録刊行物
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- 日本口腔外科学会雑誌
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日本口腔外科学会雑誌 59 (9), 588-592, 2013
社団法人 日本口腔外科学会
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詳細情報 詳細情報について
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- CRID
- 1390282681509998720
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- NII論文ID
- 130004707988
- 40019815106
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- NII書誌ID
- AN00189163
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- ISSN
- 21861579
- 00215163
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- NDL書誌ID
- 024910168
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
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- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可