機能性原子団を装置した擬タンパク質のディノボ設計

DOI Web Site Web Site 被引用文献1件 参考文献25件

書誌事項

タイトル別名
  • De novo design of pseudoproteins equipped with one of a diversity of functional groups.
  • キノウセイ ゲンシダン オ ソウチシタ ギタンパクシツ ノ ディノボ セッケイ

この論文をさがす

抄録

A pair of pyrene groups formed an excimer due to the arrangement in close proximity within a designed four-α-helix bundle structure. At the same position were incorporated a pair of flavin moieties. The oxidative activity wellworked against1-alkyldihydronicotinamide in the presence of surfactants.A porphyrin ring was also incorporated to a two-α-helix peptide. The conjugate formed a dimetic four-α-helix bundle structure with a face-to-face porphyrin arrangement. Incorporation of Fe (III) to the conjugate gave an artificial peroxidase. These pseudoproteins may evolve for artificial functions by adequate incorporation of various catalytic and photoreactive groups.

収録刊行物

  • 生物物理

    生物物理 37 (4), 161-164, 1997

    一般社団法人 日本生物物理学会

被引用文献 (1)*注記

もっと見る

参考文献 (25)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ