書誌事項
- タイトル別名
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- Development of Leukocyte–mimetic Nanoparticles to Overcome the Blood–Brain Barrier in the Region of Ischemic Stroke
- ノウコウソク ブイ ノ ケツエキ ノウ カンモン トッパ オ メザシタ ハッケッキュウ モホウ ナノ リュウシ ノ カイハツ
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説明
Drug delivery with nano–sized liposomes has been demonstrated to be useful for the treatment of cerebral ischemia/reperfusion (I/R) injury by passing through the disintegrated blood–brain barrier (BBB), whereas liposomal entry was limited at early phase after I/R. Since leukocytes can pass through the BBB by their membrane protein functions under cerebral I/R conditions, imparting leukocyte–mimicking properties to liposomes may allow the liposomes to overcome the BBB in the I/R region. In this review, we will introduce our recent findings about development of leukocyte–mimetic nanoparticles to overcome endothelial barriers, including the BBB.
収録刊行物
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- 膜
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膜 44 (5), 217-221, 2019
日本膜学会
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詳細情報 詳細情報について
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- CRID
- 1390282752342885888
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- NII論文ID
- 130007724577
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- NII書誌ID
- AN0023215X
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- ISSN
- 18846440
- 03851036
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- NDL書誌ID
- 030039553
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可