書誌事項
- タイトル別名
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- Serum Levels of IL-21 and TGF-β in the Yusho Patients
- ユショウ ニンテイ カンジャ ニ オケル IL-21,TGF-v ノ ケントウ
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説明
Aryl hydrocarbon receptor (AhR), recognized as a dioxin receptor, is expressed on the surface of helper T (Th) 17 cells. As PCBs and PCDFs are still detected in the sera of the Yusho patients, we hypothesized dysregulation of Th17 cells in the Yusho patients. In the present study, we measured IL-21 and TGF-β in the Yusho patients which induce differentiation from Th0 to Th17 cells. Serum levels of IL-21 were lower than those of controls (p < 0.05). Meanwhile, serum levels of TGF- β were decreased relative to controls, but not significant. These results may imply differentiation from Th0 cells to Th17 cells is not induced in the Yusho patients.
収録刊行物
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- 福岡醫學雜誌
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福岡醫學雜誌 104 (4), 88-90, 2013-04-25
福岡医学会
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詳細情報 詳細情報について
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- CRID
- 1390290699740728576
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- NII論文ID
- 120005303393
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- NII書誌ID
- AN00215478
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- DOI
- 10.15017/26696
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- HANDLE
- 2324/26696
- 10069/34015
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- NDL書誌ID
- 024893241
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- ISSN
- 0016254X
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- PubMed
- 23858784
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- IRDB
- NDL
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用可