Diffuse sclerosing variant of papillary thyroid carcinoma

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  • Hirata Tomoya
    Department of Head and Neck, Otorhinolaryngology, Ise Red Cross Hospital
  • Fuke Tomohito
    Department of Head and Neck, Otorhinolaryngology, Ise Red Cross Hospital
  • Kaneko Mamika
    Department of Head and Neck, Otorhinolaryngology, Ise Red Cross Hospital
  • Kobayashi Daisuke
    Department of Head and Neck, Otorhinolaryngology, Ise Red Cross Hospital
  • Yamada Hiroyuki
    Department of Head and Neck, Otorhinolaryngology, Ise Red Cross Hospital

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Other Title
  • 甲状腺びまん性硬化型乳頭癌の2例

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Description

Diffuse sclerosing variant of papillary thyroid carcinoma is a rare variant. This variant is characterized by diffuse fibrosis, calcification, abundant lymphocytic infiltration and psammoma bodies. This variant is usually seen in female patients in the second decade and has an associated chronic thyroiditis. The sonographic findings of diffuse involvement without an obvious mass in the thyroid make it often misdiagnosed as chronic thyroiditis. The treatment is total thyroidectomy, which is similar to high-risk papillary cancer, but since there are many cases with lymph node metastasis in the lateral neck, modified neck dissection is often performed. Here, we performed total thyroidectomy and modified neck dissection in two young women and added radioiodine isotope therapy postoperatively. Although the observation period was short, no recurrence was observed in either case.

Journal

  • Toukeibu Gan

    Toukeibu Gan 47 (4), 382-387, 2021

    Japan Society for Head and Neck Cancer

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