注射に代わる次世代経皮ワクチン研究の最前線 – 膜学における境界領域研究として–

DOI Web Site
  • 後藤 雅宏
    九州大学大学院工学研究院応用化学部門 九州大学次世代経皮薬物送達研究センター

書誌事項

タイトル別名
  • Recent Advances on Transdermal Vaccine as an Alternative to Injection–Boundary Regional Approach in Membrane Science and Technology–

説明

Transdermal drug delivery is receiving a growing concern to alternate conventional drug administration techniques such as oral administration or needle–stick based administration methods. In this review article, we proposed a patch system based on a solid–in–oil nanodispersion technique as a simple and efficient delivery method of drugs, especially protein and peptide vaccines, through the skin. The skin is an attractive route for vaccination because there are many immune cells. We have developed the solid–in–oil nanodisperison technique to deliver pharmaceutical bioactives efficiently through the skin. Solid–in–oil nanodispersions are nanosized drug carriers designed to overcome the skin barrier. Drug administration using a patch is user–friendly and can improve patient compliance. Protein and peptide antigen drugs were efficiently delivered across the intact skin using the solid–in–oil nanodispersions. The technique is potent transcutaneous immunization method without needles.

収録刊行物

  • 膜

    膜 48 (1), 25-30, 2023

    日本膜学会

詳細情報 詳細情報について

問題の指摘

ページトップへ