書誌事項
- タイトル別名
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- Basis of Potent Neutralizing Activity Revealed by Structural Analysis of SARS-CoV-2 Spike Proteins in Complex with Neutralizing Antibodies
説明
<p>Here, we analyzed broadly neutralizing antibodies isolated from long-term hospitalized convalescent patients of early SARS-CoV-2 strains. Antibodies named NCV2SG48 and NCV2SG53 are highly potent to broad SARS-CoV-2 variants. To reveal the mode of action, we determined the crystal structure of the Fab fragment of NCV2SG48 or NCV2SG53 in a complex with RBD of the S proteins from the Wuhan-Hu-1 and Omicron BA.1.</p>
収録刊行物
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- 日本結晶学会誌
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日本結晶学会誌 66 (2), 115-120, 2024-05-31
日本結晶学会
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詳細情報 詳細情報について
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- CRID
- 1390300456917646976
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- ISSN
- 18845576
- 03694585
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- OpenAIRE
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- 抄録ライセンスフラグ
- 使用不可