らい菌における菌体内代謝産物の動態解析

DOI Web Site Web Site 参考文献6件

書誌事項

タイトル別名
  • Dynamics of Intracellular Metabolites in <i>Mycobacterium leprae</i>
  • ライ キン ニ オケル キンタイ ナイ タイシャ サンブツ ノ ドウタイ カイセキ

この論文をさがす

説明

<p>  Mycobacterium leprae, the causative agent of leprosy, possesses unique features including inability to proliferate in vitro. In the cellular components of M. leprae, the fate of intracellular metabolites, assumed to be associated with such physiology, remain largely unknown. In this study, we found that amino acid species are significantly accumulated, while most of intermediates related to central carbon metabolism markedly decreased, in the intracellular metabolite fraction of M. leprae, as compared with that of other mycobacteria. Our results show the unique metabolite dynamics of M. leprae for the first time and these insights might contribute to understanding the physiological characteristics of leprosy.</p>

収録刊行物

参考文献 (6)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ