Bioimaging by a Scanning Probe Microscope Using Microelectrodes and Nanopipettes

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Other Title
  • 微小電極とナノピペットを利用した走査型プローブ顕微鏡によるバイオイメージング
  • ビショウ デンキョク ト ナノピペット オ リヨウ シタ ソウサガタ プローブ ケンビキョウ ニ ヨル バイオイメージング

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Abstract

<p>Scanning probe microscopy is an effective tool for nanoscale imaging and characterization at a solid-liquid interface. Scanning electrochemical microscopy (SECM) and the scanning ion conductance microscopy (SICM) using microelectrodes and nanopipettes as probes are applied to cell surface chemical and topographical imaging, respectively. In this review, we introduce our recent study concerning the development of nanoscale electrodes and a system for high-resolution of SECM, electrochemical imaging of membrane proteins, electrochemical evaluation of differentiation state of embryonic stem cells, hybrid system of SECM and SICM, neurotransmitters measurement, high-speed SICM, and chemical field effect transistor.</p>

Journal

  • BUNSEKI KAGAKU

    BUNSEKI KAGAKU 68 (1), 33-41, 2019-01-05

    The Japan Society for Analytical Chemistry

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