Primary mucinous carcinoma of the skin invading the occipital bone : a case report

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  • KUBO Tamaki
    Departments of Dermatology, Faculty of Medicine, University of Miyazaki
  • INOUE Tomohiro
    Departments of Dermatology, Faculty of Medicine, University of Miyazaki
  • UCHIDA Nozomi
    Departments of Dermatology, Faculty of Medicine, University of Miyazaki
  • SASAKI Ryoko
    Departments of Dermatology, Faculty of Medicine, University of Miyazaki
  • MOCHIDA Kousuke
    Departments of Dermatology, Faculty of Medicine, University of Miyazaki
  • SAITO Kiyotaka
    Departments of Neurosurgery, Faculty of Medicine, University of Miyazaki
  • OHISHI Ou
    Departments of Plastic and Reconstructive Surgery, Faculty of Medicine, University of Miyazaki
  • MORINAGA Keigo
    Departments of Plastic and Reconstructive Surgery, Faculty of Medicine, University of Miyazaki
  • UMEKITA Keiko
    Division of Pathophysiology, Department of Pathology, Faculty of Medicine, University of Miyazaki
  • MORIGUCHI Sayaka
    Division of Pathophysiology, Department of Pathology, Faculty of Medicine, University of Miyazaki
  • MARUTSUKA Kousuke
    Department of Pathology, Miyazaki Prefectual Miyazaki Hospital
  • AMANO Masahiro
    Departments of Dermatology, Faculty of Medicine, University of Miyazaki

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  • 頭蓋骨浸潤を来した後頭部primary mucinous carcinoma of the skinの1例

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<p>A 57-year-old woman presented with a 1-year history of a gradually enlarging solid tumor in the occipital region. Histopathological findings revealed that nests of adeno-carcinomatous tumor cells, floating in the mucinous cystic foci located in the dermis. The tumor cells were immunohistochemically positive for Cytokeratin (CK) 7 and negative for CK 20. Computed tomography (CT) showed osteolytic change of the cranial bone under the tumor. No evidence of distant metastases was found in whole body examination using positron emission tomography-computed tomography (PET-CT). The patient was diagnosed with primary mucinous carcinoma of the skin (PMCS) based on the histological and systemic examinations. Radical tumor excision and occipital scalp reconstruction by artificial bone replacement and occipital artery flap were performed. There is no evidence of tumor recurrence or metastasis 3 years after the surgery.[Skin Cancer (Japan) 2020 ; 35 : 20-26]</p>

Journal

  • Skin Cancer

    Skin Cancer 35 (1), 20-26, 2020

    The Japanese Skin Cancer Society

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