Cyclic Sulfamidite as Simultaneous Protecting Group for Amino Alcohols: Development of a Mild Deprotection Protocol Using Thiophenol
-
- Sakata Juri
- Graduate School of Pharmaceutical Sciences, Tohoku University
-
- Akita Kazunari
- Graduate School of Pharmaceutical Sciences, Tohoku University
-
- Sato Manabu
- Graduate School of Pharmaceutical Sciences, Tohoku University
-
- Shimomura Masashi
- Graduate School of Pharmaceutical Sciences, Tohoku University
-
- Tokuyama Hidetoshi
- Graduate School of Pharmaceutical Sciences, Tohoku University
この論文をさがす
説明
<p>This study describes the novel utility of cyclic sulfamidite as a simultaneous protecting group for 1,2- or 1,3-amino alcohols. An exceptionally mild and neutral condition for the removal of the cyclic sulfamidite was developed. The deprotection condition demonstrated a broad range of functional-group compatibility, including a substrate bearing a Z-enyne structure without any loss of double-bond stereochemistry.</p>
収録刊行物
-
- ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ
-
ＣＨＥＭＩＣＡＬ ＆ ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ ＢＵＬＬＥＴＩＮ 68 (10), 996-1000, 2020-10-01
公益社団法人 日本薬学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390567172583424000
-
- NII論文ID
- 130007920334
-
- NII書誌ID
- AA00602100
-
- ISSN
- 13475223
- 00092363
-
- NDL書誌ID
- 030662161
-
- PubMed
- 32999152
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
-
- 抄録ライセンスフラグ
- 使用不可
