A Case of Gastric Cancer Derived from Ectopic Pancreas and Differentiated into Adenocarcinoma with Enteroblastic Differentiation

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  • Yada Mayu
    Department of Gastroenterology, Juntendo University, School of Medicine
  • Fukushima Hirofumi
    Department of Gastroenterology, Juntendo University, School of Medicine
  • Yatagai Noboru
    Department of Gastroenterology, Juntendo University, School of Medicine
  • Murakami Takashi
    Department of Gastroenterology, Juntendo University, School of Medicine
  • Ueyama Hiroya
    Department of Gastroenterology, Juntendo University, School of Medicine
  • Shibuya Tomoyoshi
    Department of Gastroenterology, Juntendo University, School of Medicine
  • Hojyo Mariko
    Department of Gastroenterology, Juntendo University, School of Medicine
  • Yao Takashi
    Department of Human Pathology, Juntendo University, School of Medicine
  • Nagahara Akihito
    Department of Gastroenterology, Juntendo University, School of Medicine

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Other Title
  • 異所性膵由来で胎児消化管上皮類似癌に分化した胃癌の1例

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Abstract

<p>A male in his 30's, did an abdominal X-ray as population-based screening, a submucosal tumor-like projection of about 20 mm in size of the lower body of the stomach was detected. Esophagogastroduodenoscopy revealed a submucosal lesion with a depression on the top. No tumor cells were detected by biopsy, and malignant findings were considered by endoscopic ultrasound (EUS). Adenocarcinoma was diagnosed by EUS fine needle aspiration biopsy (FNAB). No metastasis was observed, and curative resection was performed with distal gastrectomy and Billroth I reconstruction. Histopathology indicated that the resected specimens revealed gastric cancer arising from the ectopic pancreas. Postoperative 15 months, liver metastasis was observed, and partial resection of the liver was performed. As a result of partial hepatectomy, the patient was diagnosed with adenocarcinoma with enteroblastic differentiation (ACED). He has been without recurrence or metastasis 18 months after hepatectomy.</p>

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