Clinical Outcomes of Treatment for Hypopharyngeal Cancer at Tokushima University Hospital

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  • 当科における下咽頭癌の治療成績
  • トウ カ ニ オケル カイントウ ガン ノ チリョウ セイセキ

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<p>In the present retrospective study, a total of 44 patients with hypopharyngeal cancer who had received their primary treatment at the Department of Otolaryngology Head and Neck Surgery, Tokushima University Hospital, between July 2010 and June 2015 were enrolled. The five-year overall survival and disease-specific survival (DSS) rates were 53% and 65%, respectively. In the 41 patients who underwent radical treatment (median follow-up period: 64 months), the T status was identified as an independent predictor of the DSS and distant metastasis-free survival (DMFS) rates, and the N status was found to be an independent predictor of the DSS, regional control, and DMFS rates. The five-year DMFS rate in the patients with T3 or T4 disease who had undergone total pharyngolaryngectomy (TPL) after induction chemotherapy (ICT) was significantly higher (67%) than that in the patients who had undergone TPL alone (33%). This finding suggests that ICT may suppress distant metastasis in patients with advanced, but resectable, hypopharyngeal cancer.</p>

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