イピリムマブ・ニボルマブ併用療法が著効した乳頭状腎細胞癌の1例

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タイトル別名
  • A Case of Pappilary Renal Cell Caircinoma which Responded Well to the Combination Therapy of Ipilimumab and Nivolumab --A CASE REPORT--
  • イピリムマブ ・ ニボルマブ ヘイヨウ リョウホウ ガ チョコウシタ ニュウトウジョウジンサイボウガン ノ 1レイ

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We report a case of papillary renal cell carcinoma that responded well to the combination of ipilimumab and nivolumab. The patient was a 68-year-old male who was being followed up for a small left renal mass without treatment. Two years later, computed tomography (CT) showed enlarged cervical and para-aortic lymph nodes, and lymph node biopsy suggested metastases of the cancer. After resection of the renal tumor, we performed pararenal aortic lymph node biopsy, and we diagnosed the case as papillary renal cell carcinoma type 1 with lymph node metastasis. The combination of ipilimumab and nivolumab each metastatic site showed regression on CT. Since immune-related adverse events occurred during the therapy nivolumab was discontinued, but partial response of the metastases was maintained.

収録刊行物

  • 泌尿器科紀要

    泌尿器科紀要 68 (4), 107-111, 2022-04-30

    泌尿器科紀要刊行会

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