CLINICAL MANIFESTATIONS AND SAFETY OF AN ORAL FOOD CHALLENGE USING BOILED EGG YOLK

DOI Web Site PubMed
  • Uneoka Kei
    Department of Allergy, Miyagi Children's Hospital
  • Horino Satoshi
    Department of Allergy, Miyagi Children's Hospital
  • Miyabayashi Hiroki
    Department of Allergy, Miyagi Children's Hospital
  • Nihei Masato
    Department of Allergy, Miyagi Children's Hospital Department of Pediatrics, South Miyagi Medical Center
  • Aki Haruka
    Department of Allergy, Miyagi Children's Hospital
  • Kitazawa Hiroshi
    Department of Allergy, Miyagi Children's Hospital Division of Pediatrics, Tohoku Medical and Pharmaceutical University
  • Miura Katsushi
    Department of Allergy, Miyagi Children's Hospital

Bibliographic Information

Other Title
  • 固ゆで卵黄の食物経口負荷試験の臨床的特徴と安全性に関する検討
  • コユ デ ランオウ ノ ショクモツ ケイコウ フカ シケン ノ リンショウテキ トクチョウ ト アンゼンセイ ニ カンスル ケントウ

Search this article

Abstract

<p>Background: Allergenicity to heated egg yolks is known to be low in hen's egg allergy. However, there are few reports concerning the safety of an oral food challenge (OFC) with boiled egg yolks. This study aimed to determine the safety of a boiled egg yolk OFC and the clinical characteristics of patients who were OFC-positive.</p><p>Methods: We retrospectively examined the data of patients who underwent an OFC with one boiled egg yolk at Miyagi Children's Hospital between January 2013 and December 2020. Patients were included if they had a history of immediate symptoms due to hen's egg or positive specific IgE levels to egg yolk or egg white.</p><p>Results: Among 600 patients, 15.0% were positive for OFC, only one patient required an intramuscular adrenaline injection, and 70% of OFC-positive patients had gastrointestinal symptoms.</p><p>Conclusion: Boiled egg yolk OFC had a low symptom induction rate; however, when symptoms were induced, gastrointestinal symptoms were most commonly observed. Given the low risk of developing severe symptoms, we conclude that the likelihood of safely performing an OFC is high.</p>

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top