A Case of Pulmonary Nocardiosis Caused by Trimethoprim-Sulfamethoxazole-Resistant <i>Nocardia wallacei</i> treated with Clavulanic acid/Amoxicillin

DOI Web Site 18 References Open Access
  • NAKAZAWA Megumi
    Department of General Internal Medicine, Kitakyushu Municipal Medical Center
  • YOKOYAMA Takashi
    Department of General Internal Medicine, Kitakyushu Municipal Medical Center
  • SATO Yoriko
    Department of General Internal Medicine, Kitakyushu Municipal Medical Center
  • NISHIDA Ruriko
    Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Science
  • UCHIDA Yujiro
    Department of General Internal Medicine, Kitakyushu Municipal Medical Center

Bibliographic Information

Other Title
  • ST合剤耐性の<i>Nocardia wallacei</i>による肺ノカルジア症をclavulanic acid/amoxicillinで治療しえた1例

Search this article

Description

<p>An 86-year-old woman with a 6-year history of bronchiectasis and recurrent pneumonia in the right lung presented to our hospital with a several weeks' history of bloody sputum. Imaging studies showed ground-glass and infiltrative opacities in the right lung, and Nocardia species were repeatedly isolated on sputum culture testing. Genetic testing identified Nocardia wallacei, which was resistant to sulfamethoxazole/trimethoprim. Therefore, the patient was treated with clavulanic acid/amoxicillin (CVA/AMPC) for a total of 6 months, and the symptoms, including the bloody sputum and cough, as well as the imaging findings, improved. Pulmonary nocardiosis can occur in patients with chronic lung disorders such as bronchiectasis, even in the absence of immunodeficiencies. Trimethoprim-sulfamethoxazole is the drug of first choice for nocardiosis, but identification of the Nocardia species and susceptibility testing are recommended for treatment, because the susceptibility varies with the species.</p>

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 97 (4), 136-140, 2023-07-20

    The Japanese Association for Infectious Diseases

References(18)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top